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The role of PCSK9 in NAFLD/NASH and therapeutic implications of PCSK9 inhibition

Mice engineered to have hyper-long telomeres have less DNA damage with aging, lower LDL cholesterol levels, and better glucose tolerance

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Systemic effects less commonly include mild dizziness or lightheadedness (may be copper-related), temporary nausea or headache (typically resolves within hours), mild fatigue (rare, reported with higher doses), and transient flu-like symptoms (very rare, may relate to systemic inflammatory response)